Differential insulin sensitivity of NMR-based metabolomic measures in a two-step hyperinsulinemic euglycemic clamp study

BACKGROUND: Insulin is the key regulator of glucose metabolism, but it is difficult to dissect direct insulin from glucose-induced effects. We aimed to investigate the effects of hyperinsulemia on metabolomic measures under euglycemic conditions in nondiabetic participants. METHODS: We assessed conc...

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Detalhes bibliográficos
Publicado no:Metabolomics
Main Authors: Wang, Wenyi, van Dijk, Ko Willems, Wijsman, Carolien A., Rozing, Maarten P., Mooijaart, Simon P., Beekman, Marian, Slagboom, P. Eline, Jukema, J. Wouter, Noordam, Raymond, van Heemst, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190027/
https://ncbi.nlm.nih.gov/pubmed/34106350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-021-01806-2
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