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An Observation on Enhanced Extracellular Acidification and Lactate Production Induced by Inhibition of Lactate Dehydrogenase A

The Warburg effect, representing enhanced glycolysis and lactate production in adequately oxygenated cancer cells, has been widely regarded to cause increased extracellular acidification. Converting pyruvate to lactate by lactate dehydrogenase A (LDHA) is the last step of glycolysis. Here, we report...

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Foilsithe in:Adv Exp Med Biol
Main Authors: Jiang, Jinxia, Roman, Jeffrey, Xu, He N., Li, Lin Z.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8189668/
https://ncbi.nlm.nih.gov/pubmed/33966212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-030-48238-1_26
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