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Targeting Unique Biological Signals on the Fly to Improve MS/MS Coverage and Identification Efficiency in Metabolomics

When using liquid chromatography/mass spectrometry (LC/MS) to perform untargeted metabolomics, it is common to detect thousands of features from a biological extract. Although it is impractical to collect non-chimeric MS/MS data for each in a single chromatographic run, this is generally unnecessary...

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Bibliografische gegevens
Gepubliceerd in:Anal Chim Acta
Hoofdauteurs: Cho, Kevin, Schwaiger-Haber, Michaela, Naser, Fuad J., Stancliffe, Ethan, Sindelar, Miriam, Patti, Gary J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8189644/
https://ncbi.nlm.nih.gov/pubmed/33551064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2021.338210
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