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Insight into the LFA-1/SARS-CoV-2 Orf7a Complex by Protein–Protein Docking, Molecular Dynamics, and MM-GBSA Calculations

[Image: see text] In the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) genome, open reading frames (ORFs) encode for viral accessory proteins. Among these, Orf7a structurally resembles the members of the immunoglobulin (Ig) superfamily and intracellular adhesion molecules (ICAMs), in...

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Dades bibliogràfiques
Publicat a:J Chem Inf Model
Autors principals: Ongaro, Alberto, Oselladore, Erika, Memo, Maurizio, Ribaudo, Giovanni, Gianoncelli, Alessandra
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2021
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8189040/
https://ncbi.nlm.nih.gov/pubmed/34043356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.1c00198
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