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Porphyrins produced by acneic Cutibacterium acnes strains activate the inflammasome by inducing K(+) leakage
Some Cutibacterium acnes subgroups dominate on healthy skin, whereas others are frequently acne associated. Here we provide mechanistic insights into this difference, using an anaerobic keratinocyte-sebocyte-C. acnes co-culture model. An acneic C. acnes strain as well as its porphyrins activates NRL...
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| Izdano u: | iScience |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8188554/ https://ncbi.nlm.nih.gov/pubmed/34151228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102575 |
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