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Propionate induces intestinal oxidative stress via Sod2 propionylation in zebrafish

Propionate and propionyl-CoA accumulation have been associated with the development of mitochondrial dysfunction. In this study, we show that propionate induces intestinal damage in zebrafish when fed a high-fat diet (HFD). The intestinal damage was associated with oxidative stress owing to compromi...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Ding, Qianwen, Zhang, Zhen, Li, Yu, Liu, Hongliang, Hao, Qiang, Yang, Yalin, Ringø, Einar, Olsen, Rolf Erik, Clarke, Jihong Liu, Ran, Chao, Zhou, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188496/
https://ncbi.nlm.nih.gov/pubmed/34142031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102515
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