Flightless I is a catabolic factor of chondrocytes that promotes hypertrophy and cartilage degeneration in osteoarthritis

Synovial macrophages that are activated by cartilage fragments initiate synovitis, a condition that promotes hypertrophic changes in chondrocytes leading to cartilage degeneration in OA. In this study, we analyzed the molecular response of chondrocytes under condition of this type of stimulation to...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Ebata, Taku, Terkawi, Mohamad Alaa, Hamasaki, Masanari, Matsumae, Gen, Onodera, Tomohiro, Aly, Mahmoud Khamis, Yokota, Shunichi, Alhasan, Hend, Shimizu, Tomohiro, Takahashi, Daisuke, Homan, Kentaro, Kadoya, Ken, Iwasaki, Norimasa
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8187833/
https://ncbi.nlm.nih.gov/pubmed/34142066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102643
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