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Biostatistical prediction of genes essential for growth of Anaplasma phagocytophilum in a human promyelocytic cell line using a random transposon mutant library

Anaplasma phagocytophilum (Ap), agent of human anaplasmosis, is an intracellular bacterium that causes the second most common tick-borne illness in North America. To address the lack of a genetic system for these pathogens, we used random Himar1 transposon mutagenesis to generate a library of Ap mut...

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Detalhes bibliográficos
Publicado no:Pathog Dis
Main Authors: O'Conor, M Catherine, Herron, Michael J, Nelson, Curtis M, Barbet, Anthony F, Crosby, F Liliana, Burkhardt, Nicole Y, Price, Lisa D, Brayton, Kelly A, Kurtti, Timothy J, Munderloh, Ulrike G
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8187696/
https://ncbi.nlm.nih.gov/pubmed/34077527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftab029
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