Role of P2X7 Receptors in Immune Responses During Neurodegeneration

P2X7 receptors are ion-gated channels activated by ATP. Under pathological conditions, the extensive release of ATP induces sustained P2X7 receptor activation, culminating in induction of proinflammatory pathways with inflammasome assembly and cytokine release. These inflammatory conditions, whether...

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Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Oliveira-Giacomelli, Ágatha, Petiz, Lyvia Lintzmaier, Andrejew, Roberta, Turrini, Natalia, Silva, Jean Bezerra, Sack, Ulrich, Ulrich, Henning
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8187565/
https://ncbi.nlm.nih.gov/pubmed/34122013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.662935
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