Arrhythmogenic and antiarrhythmic actions of late sustained sodium current in the adult human heart

Late sodium current (late INa) inhibition has been proposed to suppress the incidence of arrhythmias generated by pathological states or induced by drugs. However, the role of late INa in the human heart is still poorly understood. We therefore investigated the role of this conductance in arrhythmia...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ton, Anh Tuan, Nguyen, William, Sweat, Katrina, Miron, Yannick, Hernandez, Eduardo, Wong, Tiara, Geft, Valentyna, Macias, Andrew, Espinoza, Ana, Truong, Ky, Rasoul, Lana, Stafford, Alexa, Cotta, Tamara, Mai, Christina, Indersmitten, Tim, Page, Guy, Miller, Paul E., Ghetti, Andre, Abi-Gerges, Najah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8187365/
https://ncbi.nlm.nih.gov/pubmed/34103608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91528-1
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