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Statistical methods for mediation analysis in the era of high-throughput genomics: Current successes and future challenges

Mediation analysis investigates the intermediate mechanism through which an exposure exerts its influence on the outcome of interest. Mediation analysis is becoming increasingly popular in high-throughput genomics studies where a common goal is to identify molecular-level traits, such as gene expres...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Zeng, Ping, Shao, Zhonghe, Zhou, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8187160/
https://ncbi.nlm.nih.gov/pubmed/34141140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.05.042
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