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Different roles for the adjoining and structurally similar A-rich and poly(A) domains of oskar mRNA: only the A-rich domain is required for oskar noncoding RNA function, which includes MTOC positioning

Drosophila oskar (osk) mRNA has both coding and noncoding functions, with the latter required for progression through oogenesis. Noncoding activity is mediated by the osk 3’ UTR. Three types of cis elements act most directly and are clustered within the final ~120 nucleotides of the 3’ UTR: multiple...

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Bibliographische Detailangaben
Veröffentlicht in:Dev Biol
Hauptverfasser: Kenny, Andrew, Morgan, Miles B., Macdonald, Paul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186867/
https://ncbi.nlm.nih.gov/pubmed/33798537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2021.03.021
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