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Spatial distribution of lamin A/C determines nuclear stiffness and stress-mediated deformation

While diverse cellular components have been identified as mechanotransduction elements, the deformation of the nucleus itself is a critical mechanosensory mechanism, implying that nuclear stiffness is essential in determining responses to intracellular and extracellular stresses. Although the nuclea...

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Vydáno v:J Cell Sci
Hlavní autoři: Srivastava, Luv Kishore, Ju, Zhaoping, Ghagre, Ajinkya, Ehrlicher, Allen J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186481/
https://ncbi.nlm.nih.gov/pubmed/34028539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.248559
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