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Structure of a dimer of the Sulfolobus solfataricus MCM N-terminal domain reveals a potential role in MCM ring opening

Cells strongly regulate DNA replication to ensure genomic stability and prevent several diseases, including cancers. Eukaryotes and archaea strictly control DNA-replication initiation by the regulated loading of hexameric minichromosome maintenance (MCM) rings to encircle both strands of the DNA dou...

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Détails bibliographiques
Publié dans:Acta Crystallogr F Struct Biol Commun
Auteurs principaux: Meagher, Martin, Spence, Madison N., Enemark, Eric J.
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186412/
https://ncbi.nlm.nih.gov/pubmed/34100776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X21005331
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