Context-dependent stabilizing interactions among solvent-exposed residues along the surface of a trimeric helix bundle

Here we show that a solvent-exposed f-position (i.e., residue 14) within a well-characterized trimeric helix bundle can facilitate a stabilizing long-range synergistic interaction involving b-position Glu10 (i.e., i–4 relative to residue 14) and c-position Lys18 (i.e., i+4), depending the identity o...

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Publicado en:Biochemistry
Autores principales: Stern, Kimberlee L., Smith, Mason S., Billings, Wendy M., Loftus, Taylor J., Conover, Benjamin M., Della Corte, Dennis, Price, Joshua L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186286/
https://ncbi.nlm.nih.gov/pubmed/32270676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00045
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