The deletion of glucagon-like peptide-1 receptors expressing neurons in the dorsomedial hypothalamic nucleus disrupts the diurnal feeding pattern and induces hyperphagia and obesity

BACKGROUND: Feeding rhythm disruption contributes to the development of obesity. The receptors of glucagon-like peptide-1 (GLP-1) are distributed in the wide regions of the brain. Among these regions, GLP-1 receptors (GLP-1R) are expressed in the dorsomedial hypothalamic nucleus (DMH) which are know...

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Detalhes bibliográficos
Publicado no:Nutr Metab (Lond)
Main Authors: Maejima, Yuko, Yokota, Shoko, Shimizu, Masaru, Horita, Shoichiro, Kobayashi, Daisuke, Hazama, Akihiro, Shimomura, Kenju
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8186199/
https://ncbi.nlm.nih.gov/pubmed/34098999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-021-00582-z
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