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Increased Glutamine in Patients Undergoing Long-term Treatment for Schizophrenia: A Proton Magnetic Resonance Spectroscopy Study at 3 T
IMPORTANCE: The N-methyl-d-aspartic acid receptor hypofunction model of schizophrenia predicts a paradoxical increase in synaptic glutamate release. In vivo measurement of glutamatergic neurotransmission in humans is challenging, but glutamine, the principal metabolite of synaptic glutamate, can be...
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| Publicado no: | JAMA Psychiatry |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8185982/ https://ncbi.nlm.nih.gov/pubmed/24402128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2013.3939 |
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