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Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis

BACKGROUND: Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events including sinus node dysfunction (SND) and atrioventricular block have been previousl...

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Detalles Bibliográficos
Publicado en:BMC Neurol
Main Authors: Shibata, Makoto, Hoshino, Reona, Shimizu, Chisato, Sato, Masayuki, Furuta, Natsumi, Ikeda, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185934/
https://ncbi.nlm.nih.gov/pubmed/34102997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-021-02253-1
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