Identification of Rigosertib for the Treatment of Recessive Dystrophic Epidermolysis Bullosa–Associated Squamous Cell Carcinoma

PURPOSE: Squamous cell carcinoma (SCC) of the skin is the leading cause of death in patients with the severe generalized form of the genetic disease recessive dystrophic epidermolysis bullosa (RDEB). Although emerging data are identifying why patients suffer this fatal complication, therapies for tr...

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Pubblicato in:Clin Cancer Res
Autori principali: Atanasova, Velina S., Pourreyron, Celine, Farshchian, Mehdi, Lawler, Michael, Brown, Christian A., Watt, Stephen A., Wright, Sheila, Warkala, Michael, Guttmann-Gruber, Christina, Hofbauer, Josefina Piñón, Fuentes, Ignacia, Prisco, Marco, Rashidghamat, Elham, Has, Cristina, Salas-Alanis, Julio C., Palisson, Francis, Hovnanian, Alain, McGrath, John A., Mellerio, Jemima E., Bauer, Johann W., South, Andrew P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185613/
https://ncbi.nlm.nih.gov/pubmed/30846478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2661
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