Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau

Alzheimer’s disease is characterized by β‐amyloid plaques and tau tangles. Plasma levels of phospho‐tau217 (P‐tau217) accurately differentiate Alzheimer’s disease dementia from other dementias, but it is unclear to what degree this reflects β‐amyloid plaque accumulation, tau tangle accumulation, or...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Mattsson‐Carlgren, Niklas, Janelidze, Shorena, Bateman, Randall J, Smith, Ruben, Stomrud, Erik, Serrano, Geidy E, Reiman, Eric M, Palmqvist, Sebastian, Dage, Jeffrey L, Beach, Thomas G, Hansson, Oskar
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185545/
https://ncbi.nlm.nih.gov/pubmed/33949133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202114022
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