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ER-mitochondria contact sites in neurodegeneration: genetic screening approaches to investigate novel disease mechanisms

Mitochondria-ER contact sites (MERCS) are known to underpin many important cellular homoeostatic functions, including mitochondrial quality control, lipid metabolism, calcium homoeostasis, the unfolded protein response and ER stress. These functions are known to be dysregulated in neurodegenerative...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Wilson, Emma Louise, Metzakopian, Emmanouil
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185109/
https://ncbi.nlm.nih.gov/pubmed/33335290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00705-8
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