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A new perspective on the immune escape mechanism in HCC: onco-foetal reprogramming
We found a shared immunosuppressive microenvironment between foetal liver and hepatocellular carcinoma (HCC) which includes the re-emergence of foetal-associated endothelial cells (PLVAP/VEGFR2) and foetal-like (FOLR2) tumour-associated macrophages in HCC, mediated via VEGF–NOTCH signalling. The dis...
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| Publicado no: | Br J Cancer |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8185081/ https://ncbi.nlm.nih.gov/pubmed/33767421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-021-01286-0 |
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