Autofluorescence as a noninvasive biomarker of senescence and advanced glycation end products in Caenorhabditis elegans

To assess the utility of autofluorescence as a noninvasive biomarker of senescence in Caenorhabditis elegans, we measured the autofluorescence of individual nematodes using spectrofluorometry. The fluorescence of each worm increased with age. Animals with lower fluorescence intensity exhibited longe...

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Bibliografiske detaljer
Udgivet i:NPJ Aging Mech Dis
Main Authors: Komura, Tomomi, Yamanaka, Mikihiro, Nishimura, Kohji, Hara, Keita, Nishikawa, Yoshikazu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184826/
https://ncbi.nlm.nih.gov/pubmed/34099724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41514-021-00061-y
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