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Selective estrogen receptor modulator lasofoxifene suppresses spondyloarthritis manifestation and affects characteristics of gut microbiota in zymosan-induced SKG mice

Ankylosing spondylitis is a male-predominant disease and previous study revealed that estrogens have an anti-inflammatory effect on the spondyloarthritis (SpA) manifestations in zymosan-induced SKG mice. This study aimed to evaluate the effect of selective estrogen receptor modulator (SERM) lasofoxi...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Jeong, Hyemin, Kim, In Young, Bae, Eun-Kyung, Jeon, Chan Hong, Ahn, Kwang-Sung, Cha, Hoon-Suk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184804/
https://ncbi.nlm.nih.gov/pubmed/34099783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91320-1
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