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Pharmacokinetics and pharmacodynamics of ampreloxetine, a novel, selective norepinephrine reuptake inhibitor, in symptomatic neurogenic orthostatic hypotension

PURPOSE: Ampreloxetine is a novel, selective, long-acting norepinephrine reuptake (NET) inhibitor being investigated as a once-daily oral treatment for symptomatic neurogenic orthostatic hypotension (nOH) in patients with autonomic synucleinopathies. The purpose of this study was to characterize the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Auton Res
Hauptverfasser: Lo, Arthur, Norcliffe-Kaufmann, Lucy, Vickery, Ross, Bourdet, David, Kanodia, Jitendra
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184714/
https://ncbi.nlm.nih.gov/pubmed/33782836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10286-021-00800-x
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