Next Generation Polyphosphazene Immunoadjuvant: Synthesis, Self-Assembly and In Vivo Potency with Human Papillomavirus VLPs-Based Vaccine

Poly[di(carboxylatomethylphenoxy)phosphazene], PCMP - a new member of polyphosphazene immunoadjuvant family is synthesized. In vitro assessment of a new macromolecule revealed hydrolytic degradation profile and immunostimulatory activity comparable to its clinical stage homologue - PCPP, however PCM...

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Publicado en:Nanomedicine
Autores principales: Marin, Alexander, Chowdhury, Ananda, Valencia, Sarah M., Zacharia, Athina, Kirnbauer, Reinhard, Roden, Richard B.S., Pinto, Ligia A., Shoemaker, Robert H., Marshall, Jason D., Andrianov, Alexander K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184581/
https://ncbi.nlm.nih.gov/pubmed/33476764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2021.102359
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