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Cbl-b is upregulated and plays a negative role in activated human NK cells
The E3 ubiquitin ligase Cbl-b has been characterized as an intracellular checkpoint in T cells; however, the function of Cbl-b in primary human natural killer (NK) cells, an innate immune anti-tumor effector cell, is not well defined. Here we show that the expression of Cbl-b is significantly upregu...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8184061/ https://ncbi.nlm.nih.gov/pubmed/33419766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000177 |
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