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Sex and kidney ACE2 expression in primary focal segmental glomerulosclerosis: A NEPTUNE study

BACKGROUND: Angiotensin-converting enzyme 2 (ACE2) has been implicated in the pathogenesis of experimental kidney disease. ACE2 is on the X chromosome, and in mice, deletion of ACE2 leads to the development of focal segmental glomerulosclerosis (FSGS). The relationship between sex and renal ACE2 exp...

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Publicat a:PLoS One
Autors principals: Maksimowski, Nicholas A., Scholey, James W., Williams, Vanessa R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184004/
https://ncbi.nlm.nih.gov/pubmed/34097714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0252758
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