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Malic Enzyme Couples Mitochondria with Aerobic Glycolysis in Osteoblasts

The metabolic program of osteoblasts, the chief bone-making cells, remains incompletely understood. Here in murine calvarial cells, we establish that osteoblast differentiation under aerobic conditions is coupled with a marked increase in glucose consumption and lactate production but reduced oxygen...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Lee, Wen-Chih, Ji, Xing, Nissim, Itzhak, Long, Fanxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8183612/
https://ncbi.nlm.nih.gov/pubmed/32905773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108108
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