Persistent NF-κB activation in muscle stem cells induces proliferation-independent telomere shortening

During the repeated cycles of damage and repair in many muscle disorders, including Duchenne muscular dystrophy (DMD), the muscle stem cell (MuSC) pool becomes less efficient at responding to and repairing damage. The underlying mechanism of such stem cell dysfunction is not fully known. Here, we de...

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Publicado no:Cell Rep
Main Authors: Tichy, Elisia D., Ma, Nuoying, Sidibe, David, Loro, Emanuele, Kocan, Jacob, Chen, Delia Z., Khurana, Tejvir S., Hasty, Paul, Mourkioti, Foteini
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8183356/
https://ncbi.nlm.nih.gov/pubmed/33979621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109098
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