Persistent NF-κB activation in muscle stem cells induces proliferation-independent telomere shortening

During the repeated cycles of damage and repair in many muscle disorders, including Duchenne muscular dystrophy (DMD), the muscle stem cell (MuSC) pool becomes less efficient at responding to and repairing damage. The underlying mechanism of such stem cell dysfunction is not fully known. Here, we de...

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Publicat a:Cell Rep
Autors principals: Tichy, Elisia D., Ma, Nuoying, Sidibe, David, Loro, Emanuele, Kocan, Jacob, Chen, Delia Z., Khurana, Tejvir S., Hasty, Paul, Mourkioti, Foteini
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8183356/
https://ncbi.nlm.nih.gov/pubmed/33979621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109098
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