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NDRG1 regulates osteosarcoma cells via mediating the mitochondrial function and CSCs differentiation

BACKGROUND: Cancer stem cells (CSCs) are mainly contributed to malignancy metastatic potential and resistant therapy of osteosarcoma (OS). The mitochondria-related apoptosis was generally accepted as the target of tumor therapy. However, the effect of N-myc downstream-regulated gene 1 (NDRG1) on CSC...

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Podrobná bibliografie
Vydáno v:J Orthop Surg Res
Hlavní autoři: Zhao, Tong, Meng, Ying, Wang, Yongping, Wang, Wenji
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8182938/
https://ncbi.nlm.nih.gov/pubmed/34099022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-021-02503-5
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