Landscape of cell heterogeneity and evolutionary trajectory in ulcerative colitis-associated colon cancer revealed by single-cell RNA sequencing

OBJECTIVE: The goal of this study was to get preliminary insight on the intra-tumor heterogeneity in colitis-associated cancer (CAC) and to reveal a potential evolutionary trajectory from ulcerative colitis (UC) to CAC at the single-cell level. METHODS: Fresh samples of tumor tissues and adjacent UC...

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Veröffentlicht in:Chin J Cancer Res
Hauptverfasser: Wang, Quan, Wang, Zhu, Zhang, Zhen, Zhang, Wei, Zhang, Mengmeng, Shen, Zhanlong, Ye, Yingjiang, Jiang, Kewei, Wang, Shan
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2021
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8181874/
https://ncbi.nlm.nih.gov/pubmed/34158745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21147/j.issn.1000-9604.2021.02.13
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