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miR-373 Suppresses Cell Proliferation and Apoptosis via Regulation of SIRT1/PGC-1α/NRF2 Axis in Pancreatic Cancer

OBJECTIVE: Our study aimed to investigate function and mechanism of miR-373 in proliferation and apoptosis of pancreatic cancer (PC) cells by regulating NAD+-dependent histone deacetylase sirtulin 1 (SIRT1). MATERIALS AND METHODS: This experimental study included two PC cell lines AsPC-1 and PANC-1...

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Podrobná bibliografie
Vydáno v:Cell J
Hlavní autoři: Yin, Qing-Hua, Zhou, Yuan, Li, Zhi-Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Royan Institute 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8181315/
https://ncbi.nlm.nih.gov/pubmed/34096221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2021.7038
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