Choline Supplementation in Obese Mouse Dams Alters Offspring DNA Methylation in a Time-Specific Manner

OBJECTIVES: Maternal obesity has long-term influence on metabolic health of offspring, partly through an epigenetic mechanism. Choline is a methyl donor which provides methyl groups for epigenetic modification such as DNA methylation. In this study, we examined the effect of maternal choline supplem...

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Vydáno v:Curr Dev Nutr
Hlavní autoři: Jiang, Xinyin, Korsmo, Hunter, Dembitzer, Moshe, Khaldi, Sarah, Sheeraz, Shameera
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Maternal, Perinatal and Pediatric Nutrition
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8181269/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzab046_060
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