Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1

BACKGROUND: Androgen deprivation therapy (ADT) is the main clinical treatment for patients with advanced prostate cancer (PCa). However, PCa eventually progresses to castration‐resistant prostate cancer (CRPC), largely because of androgen receptor variation and increased intratumoral androgen synthe...

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Bibliografiske detaljer
Udgivet i:Clin Transl Med
Main Authors: Zhou, Lijie, Zhang, Cai, Yang, Xiong, Liu, Lilong, Hu, Junyi, Hou, Yaxin, Tao, Hong, Sugimura, Haruhiko, Chen, Zhaohui, Wang, Liang, Chen, Ke
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8181204/
https://ncbi.nlm.nih.gov/pubmed/34185414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.449
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