Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1

BACKGROUND: Androgen deprivation therapy (ADT) is the main clinical treatment for patients with advanced prostate cancer (PCa). However, PCa eventually progresses to castration‐resistant prostate cancer (CRPC), largely because of androgen receptor variation and increased intratumoral androgen synthe...

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Publicado en:Clin Transl Med
Autores principales: Zhou, Lijie, Zhang, Cai, Yang, Xiong, Liu, Lilong, Hu, Junyi, Hou, Yaxin, Tao, Hong, Sugimura, Haruhiko, Chen, Zhaohui, Wang, Liang, Chen, Ke
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8181204/
https://ncbi.nlm.nih.gov/pubmed/34185414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.449
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