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p-Nitrophenyl esters provide new insights and applications for the thiolase enzyme OleA
The OleA enzyme is distinct amongst thiolase enzymes in binding two long (≥C(8)) acyl chains into structurally-opposed hydrophobic channels, denoted A and B, to carry out a non-decarboxylative Claisen condensation reaction and initiate the biosynthesis of membrane hydrocarbons and β-lactone natural...
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| Publicado no: | Comput Struct Biotechnol J |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Research Network of Computational and Structural Biotechnology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8180931/ https://ncbi.nlm.nih.gov/pubmed/34141132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.05.031 |
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