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Cochlin Deficiency Protects Against Noise-Induced Hearing Loss

Cochlin is the most abundant protein in the inner ear. To study its function in response to noise trauma, we exposed adolescent wild-type (Coch(+/+)) and cochlin knock-out (Coch(–/–)) mice to noise (8–16 kHz, 103 dB SPL, 2 h) that causes a permanent threshold shift and hair cell loss. Two weeks afte...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Seist, Richard, Landegger, Lukas D., Robertson, Nahid G., Vasilijic, Sasa, Morton, Cynthia C., Stankovic, Konstantina M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8180578/
https://ncbi.nlm.nih.gov/pubmed/34108864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.670013
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