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Suramin enhances the urinary excretion of VEGF-A in normoglycemic and streptozotocin-induced diabetic rats
BACKGROUND: Vascular endothelial growth factor A (VEGF-A) and P2-receptors (P2Rs) are involved in the pathogenesis of diabetic nephropathy. The processing of VEGF-A by matrix metalloproteinases (MMP) regulates its bioavailability. Since the ATP-induced release of MMP-9 is mediated by P2Rs, we invest...
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| Publicado no: | Pharmacol Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8180480/ https://ncbi.nlm.nih.gov/pubmed/33635529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s43440-021-00236-0 |
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