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EML4-ALK-mediated activation of the JAK2-STAT pathway is critical for non-small cell lung cancer transformation

BACKGROUND: The echinoderm microtubule-associated protein-like-4 anaplastic lymphoma kinase (EML4-ALK) fusion gene was identified in a subset of non-small cell lung cancer (NSCLC) patients. They responded positively to ALK inhibitors. This study aimed to characterize the mechanisms triggered by EML4...

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Detalhes bibliográficos
Publicado no:BMC Pulm Med
Main Authors: Li, Ying, Li, Yongwen, Zhang, Hongbing, Shi, Ruifeng, Zhang, Zihe, Liu, Hongyu, Chen, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8180148/
https://ncbi.nlm.nih.gov/pubmed/34090412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-021-01553-z
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