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Down-regulation of SNHG16 alleviates the acute lung injury in sepsis rats through miR-128-3p/HMGB3 axis

BACKGROUND: Long noncoding RNAs contribute to various inflammatory diseases, including sepsis. We explore the role of small nucleolar RNA host gene 16 (SNHG16) in sepsis-mediated acute lung injury (ALI) and inflammation. METHODS: A sepsis-induced ALI rat model was constructed by the cecal ligation a...

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Veröffentlicht in:BMC Pulm Med
Hauptverfasser: Sun, Junli, Xin, Keke, Leng, Chenghui, Ge, Jianlin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8180123/
https://ncbi.nlm.nih.gov/pubmed/34092219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-021-01552-0
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