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Xenograft and cell culture models of Sézary syndrome reveal cell of origin diversity and subclonal heterogeneity
Sézary Syndrome (SS) is a rare aggressive epidermotropic cutaneous T-cell lymphoma (CTCL) defined by erythroderma, pruritis, and a circulating atypical CD4 + T-cell clonal population. The diversity of Sézary cell (SC) phenotype and genotype may reflect either plasticity or heterogeneity, which was d...
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| 發表在: | Leukemia |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8179845/ https://ncbi.nlm.nih.gov/pubmed/33106625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-01068-2 |
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