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A controlled T7 transcription-driven symmetric amplification cascade machinery for single-molecule detection of multiple repair glycosylases

Genomic oxidation and alkylation are two of the most important forms of cytotoxic damage that may induce mutagenesis, carcinogenicity, and teratogenicity. Human 8-oxoguanine (hOGG1) and alkyladenine DNA glycosylases (hAAG) are responsible for two major forms of oxidative and alkylative damage repair...

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Publicat a:Chem Sci
Autors principals: Wang, Li-juan, Liang, Le, Liu, Bing-jie, Jiang, BingHua, Zhang, Chun-yang
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society of Chemistry 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179622/
https://ncbi.nlm.nih.gov/pubmed/34168791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc00189b
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