Towards the stable chelation of radium for biomedical applications with an 18-membered macrocyclic ligand

Targeted alpha therapy is an emerging strategy for the treatment of disseminated cancer. [(223)Ra]RaCl(2) is the only clinically approved alpha particle-emitting drug, and it is used to treat castrate-resistant prostate cancer bone metastases, to which [(223)Ra]Ra(2+) localizes. To specifically dire...

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Bibliografiska uppgifter
I publikationen:Chem Sci
Huvudupphovsmän: Abou, Diane S., Thiele, Nikki A., Gutsche, Nicholas T., Villmer, Alexandria, Zhang, Hanwen, Woods, Joshua J., Baidoo, Kwamena E., Escorcia, Freddy E., Wilson, Justin J., Thorek, Daniel L. J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Royal Society of Chemistry 2021
Ämnen:
Chemistry
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179459/
https://ncbi.nlm.nih.gov/pubmed/34163647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc06867e
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