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Rational designing of glyco-nanovehicles to target cellular heterogeneity

The aberrant expression of endocytic epidermal growth factor receptors (EGFRs) in cancer cells has emerged as a key target for therapeutic intervention. Here, we describe for the first time a state-of-the-art design for a heparan sulfate (HS) oligosaccharide-based nanovehicle to target EGFR-overexpr...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Jain, Prashant, Shanthamurthy, Chethan D., Chaudhary, Preeti Madhukar, Kikkeri, Raghavendra
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179433/
https://ncbi.nlm.nih.gov/pubmed/34163672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc00140j
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