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Investigation on the reactivity of nucleophilic radiohalogens with arylboronic acids in water: access to an efficient single-step method for the radioiodination and astatination of antibodies

Easy access to radioiodinated and (211)At-labelled bio(macro)molecules is essential to develop new strategies in nuclear imaging and targeted radionuclide therapy of cancers. Yet, the labelling of complex molecules with heavy radiohalogens is often poorly effective due to the multiple steps and inte...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Berdal, Marion, Gouard, Sébastien, Eychenne, Romain, Marionneau-Lambot, Séverine, Croyal, Mikaël, Faivre-Chauvet, Alain, Chérel, Michel, Gaschet, Joëlle, Gestin, Jean-François, Guérard, François
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179031/
https://ncbi.nlm.nih.gov/pubmed/34163909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc05191h
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