Tumor-derived exosomal microRNA-106b-5p activates EMT-cancer cell and M2-subtype TAM interaction to facilitate CRC metastasis

Epithelial-mesenchymal transition (EMT) is reported to involve in the crosstalk between tumor cells and tumor-associated macrophages (TAMs). Exosomes are considered as important mediators of orchestrating intercellular communication. However, the underlying mechanisms by which EMT-colorectal cancer...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Yang, Chaogang, Dou, Rongzhang, Wei, Chen, Liu, Keshu, Shi, Dongdong, Zhang, Chunxiao, Liu, Qing, Wang, Shuyi, Xiong, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178444/
https://ncbi.nlm.nih.gov/pubmed/33571679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2021.02.006
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