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Amino acid-based H(2)S Donors: N-Thiocarboxyanhydrides that release H(2)S with innocuous byproducts
A library of N-thiocarboxyanhydrides (NTAs) derived from natural amino acids with benign byproducts and controlled H(2)S-release kinetics is reported. Minimal acute in vitro toxicity was observed in multiple cell lines, while longer-term toxicity in cancer cells was observed, with slow-releasing don...
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| Udgivet i: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8178226/ https://ncbi.nlm.nih.gov/pubmed/33956024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1cc01309b |
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