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Roles of the BAP1 tumor suppressor in cell metabolism

BRCA1-associated protein 1 (BAP1) is emerging as an intensively studied cancer-associated gene. Germline mutations in BAP1 lead to a cancer syndrome, and somatic loss is found in several cancer types. BAP1 encodes a deubiquitinase enzyme, which plays key roles in cell cycle regulation, cell death, a...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Han, Anna, Purwin, Timothy J., Aplin, Andrew E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178170/
https://ncbi.nlm.nih.gov/pubmed/33446574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-3430
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