Monitoring epidermal growth factor receptor C797S mutation in Japanese non–small cell lung cancer patients with serial cell‐free DNA evaluation using digital droplet PCR

Osimertinib is a third‐generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR‐TKI) that is effective in treating both naïve and T790M‐mutated EGFR‐TKI‐resistant non–small cell lung cancer patients. The EGFR C797S mutation is the major osimertinib resistance mechanism. The presen...

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Publicado en:Cancer Sci
Autores principales: Ariyasu, Ryo, Uchibori, Ken, Sasaki, Takaaki, Tsukahara, Mika, Kiyotani, Kazuma, Yoshida, Ryohei, Ono, Yusuke, Kitazono, Satoru, Ninomiya, Hironori, Ishikawa, Yuichi, Mizukami, Yusuke, Yanagitani, Noriko, Fujita, Naoya, Nishio, Makoto, Katayama, Ryohei
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8177776/
https://ncbi.nlm.nih.gov/pubmed/33686722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14879
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