Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

Hepatocellular carcinoma (HCC) is driven by repeated rounds of inflammation, leading to fibrosis, cirrhosis, and, ultimately, cancer. A critical step in HCC formation is the transition from fibrosis to cirrhosis, which is associated with a change in the liver parenchyma called ductular reaction. Her...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Barthet, Valentin J. A., Brucoli, Martina, Ladds, Marcus J. G. W., Nössing, Christoph, Kiourtis, Christos, Baudot, Alice D., O’Prey, James, Zunino, Barbara, Müller, Miryam, May, Stephanie, Nixon, Colin, Long, Jaclyn S., Bird, Thomas G., Ryan, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8177709/
https://ncbi.nlm.nih.gov/pubmed/34088666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abf9141
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